Subset of the mouse osteoblast dataset, summarized to gene level.
data(osteoblast_gene_chr1)SummarizedExperiment
The dataset contains allelic counts quantified with Salmon, for two mouse crosses (B6 crossed with 129, and with CAST). The samples are from a mouse osteoblast differentiation time course from day 2 to day 18 (9 time points in total). The data has been subset to chromosome 1. See References for links to original publication, and quantification steps.
The osteoblast differentiation experiment is described here:
Kemp JP, Medina-Gomez C, Estrada K, St Pourcain B et al. Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. PLoS Genet 2014 Jun;10(6):e1004423. PMID: 24945404 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063697/
With an associated GEO series:
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE54461
The quantification steps are provided in a Snakefile here: